Rutaecarpine Side Effects
Rutaecarpine, CAS# 84-26-4, is a COX-2 inhibitor manufactured through extraction from evodia rutaecarpa, available as white powder. Rutaecarpine is widely used as nutritional supplements. It is widely accepted as safe food additive in many countries.
General Side Effects
No significant side effects reported.
Suggested Dosage
As Rutaecarpine is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Rutaecarpine for long period.
* ADI: Acceptable Daily Intake
* MTDI: maximum tolerable daily intake
* Data source: JECFA Database of WHO
Special Groups Precaution
Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
There is no evidence that Rutaecarpine could have any negative effects on these vulnerable groups. It should be safe to use Rutaecarpine in food for newborns and pregnant. However, we still recommend consumers to consult professionals before using large quantity of Rutaecarpine for long period in food for newborns or pregnant.
GRAS Affirmation: Yes
Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Rutaecarpine is considered safe by FDA according to existing data and granted GRAS status.
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