Creatine Anhydrous Side Effects

Creatine Anhydrous, CAS#57-00-1,is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.

General Side Effects

No significant side effects reported. Creatine can cause stomach pain, nausea, diarrhea, and muscle cramping in specific groups of individuals. There is some concern that creatine might make kidney disease worse.

Suggested Dosage

As Creatine Anhydrous is widely known as safe, there is no limit on dosage of intake. However, we still recommend consumers to consult professionals before using large quantity of Creatine Anhydrous for long period.
* ADI: Acceptable Daily Intake
* MTDI: maximum tolerable daily intake
* Data source: JECFA Database of WHO

Special Groups Precaution

Special groups refer to newborns, children, pregnant and any other applicable vulnerable groups.
Creatine Anhydrous may have some affect on individuals with kidney disease or diabetes. We recommend consumers to consult professionals before using Creatine Anhydrous in food of individuals with kidney disease or diabetes.

GRAS Affirmation: Yes

Generally recognized as safe(GRAS) is a FDA designation that a specific substance or ingredient is generally considered safe by experts, and so is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. Creatine Anhydrous is considered safe by FDA according to existing data and granted GRAS status.

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